Company Overview

The Company

Advanced Cell Technology, Inc., (“ACT” OTCBB: ACTC) is a biotechnology company that specializes in the development of cellular therapies for the treatment of diseases and conditions that impact tens of millions of people worldwide. The company applies stem cell-based technologies (both adult and human embryonic) and other proprietary methods in the field of regenerative medicine to bring patient-specific therapies from the lab bench to the bedside.

ACT’s principal laboratory and GMP facility is in Marlborough, Massachusetts, and its corporate offices are in Santa Monica, California. ACT is led by an experienced management team and a world-class scientific team helmed, respectively, by Interim Chairman and Chief Executive Officer Gary Rabin and Chief Scientific Officer Robert Lanza, M.D.

Therapeutic Platforms

ACT has three cellular product platforms based on ground-breaking stem cell technology. As documented in the journals Nature and Cell Stem Cell, ACT developed and holds in its repertoire the first-ever proven alternative method for successful hESC generation without harm to the embryo, called the “single-cell blastomere” technique, on which it holds broad intellectual property (IP) protection.

  • The company is focused on commercializing its human embryonic stem cell (hESC)-based Retinal Pigment Epithelial (RPE) therapy for degenerative retinal disease, for which it has recently secured two FDA clearances for Phase 1/2 clinical trials for which it recently initiated two Phase 1 clinical trials.
  • The company is also developing its human embryonic stem cell (hESC)-based Hemangioblast (HG) platform for the treatment of blood and cardiovascular diseases. The company is developing this program in partnership with CHA Biotech of Korea.
  • The company is focused on advancing its Phase 2-approved Myoblast autologous adult stem cell therapy for the treatment of chronic heart failure, advanced cardiac disease, myocardial infarction, and ischemia.